The effect of x-rays on the membrane permeability of human erythrocytes
Loading...
Authors
Garver, Richard M.
Saylor, William L.,
Subjects
Advisors
Date of Issue
1962
Date
1962
Publisher
Language
en_US
Abstract
Human erythrocytes were irradiated in order to study the effect of
x-rays on the cell membrane. The red blood cells were exposed to various
dosages of 145KVP x-rays up to 10,000 r. The effect of the x-rays on the
physical characteristics of the cell membrane was evaluated by use of an
alternating current wheatstone bridge. Changes in the rates of ion transport through the membrane were evaluated by K⁴² tracer studies. The
x-irradiation was found to have no detectable effect on the physical
characteristics of the membrane, or upon the rate of uptake of potassium;
however, x-irradiation of 10,000 r was found to cause a substantial increase
in the rate of potassium loss by the cells,. These results are
attributed to disturbance by the radiation of some intracellular process
which is involved in the maintenance of the observed ionic concentration
gradients.
Type
Thesis
Description
Series/Report No
Department
Physics
Organization
Naval Postgraduate School (U.S.)
Identifiers
NPS Report Number
Sponsors
Funder
Format
Citation
Distribution Statement
Approved for public release; distribution is unlimited.
Rights
This publication is a work of the U.S. Government as defined in Title 17, United States Code, Section 101. Copyright protection is not available for this work in the United States.