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dc.contributor.advisorDimitrov, Nedialko B.
dc.contributor.advisorSingham, Dashi
dc.contributor.authorAlok, Diwya
dc.dateMar-13
dc.date.accessioned2013-05-08T20:41:26Z
dc.date.available2013-05-08T20:41:26Z
dc.date.issued2013-03
dc.identifier.urihttp://hdl.handle.net/10945/32786
dc.description.abstractA study conducted by Carpenter, OBrien, Hagerman and McCarl in 2011 estimates the economic impact of a foot and mouth disease (FMD) epidemic in the United States to be $2.3$69.0 billion. We simulate an outbreak of FMD across central California using the InterSpread Plus simulation package. We use an experimental design that produces 102,400 epidemic simulation runs. Using the data from the simulations, we identify 16 critical disease and control parameters that have the greatest effect on the spread of FMD. A statistical model based on these 16 parameters and their interactions captures approximately 85% of the variability of the simulation model. The main takeaways of our analysis of FMD spread are as follows. The two most critical disease parameters are initial condition and local spread. The most critical disease control parameters are market movement and surveillance. Our experimental results indicate that if a typical premise sends an animal to market every 2.2 days instead of every day, we will see a 25% reduction in the mean number of cattle infected. Similarly, if there is less than a three day delay in between suspecting an FMD outbreak and declaring an FMD outbreak at dairy-like facilities, we see a 50% reduction in the number of infected cattle. Control measures cannot be taken in isolation. Our models show significant interaction effects between the most effective control measuresmarket movement, and surveillance and other control measures such as tracing, vaccination and depopulation.en_US
dc.description.urihttp://archive.org/details/ahighexplanatory1094532786
dc.publisherMonterey, California. Naval Postgraduate Schoolen_US
dc.titleA HIGH EXPLANATORY POWER MODEL OF FOOT AND MOUTH DISEASE SPREAD IN CENTRAL CALIFORNIA.en_US
dc.contributor.secondreaderSanchez, Paul
dc.contributor.departmentOperations Research
dc.subject.authorCentral Californiaen_US
dc.subject.authorFoot and mouth diseaseen_US
dc.subject.authordisease modeling softwareen_US
dc.subject.authorInterSpread Plusen_US
dc.subject.authorsimulation modelen_US
dc.subject.authordesign of experimenten_US
dc.subject.authorNOBen_US
dc.subject.authordisease parametersen_US
dc.subject.authorcontrol parametersen_US
dc.subject.authorregression modelen_US
dc.subject.authorpartition tree modelen_US
dc.subject.authorsensitivity analysisen_US
dc.description.serviceLieutenant Commander, Indian Navyen_US
etd.thesisdegree.nameMaster Of Science In Operations Researchen_US
etd.thesisdegree.levelMastersen_US
etd.thesisdegree.disciplineOperations Researchen_US
dc.description.distributionstatementApproved for public release; distribution is unlimited.


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