A comparative analysis of multivariate statistical detection methods applied to syndromic surveillance
Matthew C. Knitt.
Fricker, Ronald D.
Olwell, David H.
MetadataShow full item record
Biological terrorism is a threat to the security and well-being of the United States. It is critical to detect the presence of these attacks in a timely manner, in order to provide sufficient and effective responses to minimize or contain the damage inflicted. Syndromic surveillance is the process of monitoring public health-related data and applying statistical tests to determine the potential presence of a disease outbreak in the observed system. Our research involved a comparative analysis of two multivariate statistical methods, the multivariate CUSUM (MCUSUM) and the multivariate exponentially weighted moving average (MEWMA), both modified to look only for increases in disease incidence. While neither of these methods is currently in use in a biosurveillance system, they are among the most promising multivariate methods for this application. Our analysis was based on a series of simulations using synthetic syndromic surveillance data that mimics various types of background disease incidence and outbreaks. We found that, similar to results for the univariate CUSUM and EWMA, the directionally-sensitive MCUSUM and MEWMA perform very similarly.
Showing items related by title, author, creator and subject.
Fricker, Ronald D. Jr.; Hu, Cecilia X. (2008-02);This paper compares the performance of two new directly-sensitive multivariate methods, based on the multivariate CUSUM (MCUSUM) and the multivariate exponentially weighted moving average (MEWMA), for biosurveillance. ...
Lewis, Peter A. W.; Shedler, Gerald S. (Monterey, California. Naval Postgraduate School, 1977-09); NPS-55-77-38Models of univariate and multivariate series of events (point processes) and statistical methods for the analysis of point processes have diverse applications in the study of computer systems. These applications, which ...
A sixth-order family of three-point modified Newton-like multiple-root finders and the dynamics behind their extraneous fixed points Neta, Beny; Geum, Young Hee; Kim, Young Ik (Elsevier Inc., 2016);A class of three-point sixth-order multiple-root finders and the dynamics behind their extraneous fixed points are investigated by extending modified Newton-like methods with the introduction of the multivariate weight ...