Show simple item record

dc.contributor.advisorKwon, Young W.
dc.contributor.authorClumpner, Brandon R.
dc.dateDec-14
dc.date.accessioned2015-02-18T00:17:25Z
dc.date.available2015-02-18T00:17:25Z
dc.date.issued2014-12
dc.identifier.urihttp://hdl.handle.net/10945/44540
dc.descriptionApproved for public release; distribution is unlimiteden_US
dc.description.abstractA multiscale model was developed to link the hierarchies of human bone in different length scales. Bone has a unique structure displaying large stiffness with minimal weight. This is achieved through a hierarchy of complex geometries composed of only three materials: hydroxyapatite, collagen and water. The identifiable structures of bone are hydroxyapatite, tropocollagen, fibrils, fibers, lamellar layers, trabecular bone, cancellous bone and cortical bone. A spring model was used to evaluate the stiffness of collagen. A unit-cell based micromechanics model analyzed both the normal and shear properties of fibrils, fibers, and lamellar layers. A layered composite model assessed cortical and trabecular bone while a simple finite element model was used to evaluate cancellous bone. Modeling bone from nanoscale components to macroscale structures allows the influence of each structure to be assessed. It was found that the distribution of hydroxyapatite within the tropocollagen matrix at the fibril level influences the macroscale properties the most. Additionally, the model allows perturbations to the geometry of any hierarchy to be analyzed. With so little known about the detailed structure of nanoscale and microscale bone, a model comprising the complete hierarchy of bone can be used to help validate assumptions or hypotheses about structure.en_US
dc.description.urihttp://archive.org/details/multiscalemodeli1094544540
dc.publisherMonterey, California: Naval Postgraduate Schoolen_US
dc.rightsThis publication is a work of the U.S. Government as defined in Title 17, United States Code, Section 101. Copyright protection is not available for this work in the United States.en_US
dc.titleMultiscale modeling of boneen_US
dc.typeThesisen_US
dc.contributor.secondreaderDidoszak, Jarema M.
dc.contributor.departmentMechanical and Aerospace Engineering (MAE)
dc.subject.authormultiscale modelingen_US
dc.subject.authorbiocompositeen_US
dc.subject.authorbiomaterialsen_US
dc.subject.authortropocollagenen_US
dc.subject.authorcollagenen_US
dc.subject.authorboneen_US
dc.subject.authorhydroxyapatiteen_US
dc.subject.authorFEMen_US
dc.subject.authortetrakaidecahedronen_US
dc.subject.authorfibrilen_US
dc.subject.authortrabecularen_US
dc.subject.authorcancellousen_US
dc.subject.authorcorticalen_US
dc.description.recognitionOutstanding Thesisen_US
dc.description.serviceFirst Lieutenant, United States Armyen_US
etd.thesisdegree.nameMaster of Science in Mechanical Engineering and Mechanical Engineeren_US
etd.thesisdegree.levelMastersen_US
etd.thesisdegree.disciplineMechanical Engineeringen_US
etd.thesisdegree.grantorNaval Postgraduate Schoolen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record