Comparison of acrylamide intake from Western and guideline based diets using probabilistic techniques and linear programming

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Authors
Katz, Josh M.
Winter, Carl K.
Buttrey, Samuel E.
Fadel, James G.
Subjects
Acrylamide
Dietary guidelines
Linear programming
Dietary modeling
Advisors
Date of Issue
2012-11
Date
Publisher
Elsevier
Language
Abstract
Western and guideline based diets were compared to determine if dietary improvements resulting from following dietary guidelines reduce acrylamide intake. Acrylamide forms in heat treated foods and is a human neurotoxin and animal carcinogen. Acrylamide intake from the Western diet was estimated with probabilistic techniques using teenage (13–19 years) National Health and Nutrition Examination Survey (NHANES) food consumption estimates combined with FDA data on the levels of acrylamide in a large number of foods. Guideline based diets were derived from NHANES data using linear programming techniques to comport to recommendations from the Dietary Guidelines for Americans, 2005. Whereas the guideline based diets were more properly balanced and rich in consumption of fruits, vegetables, and other dietary components than the Western diets, acrylamide intake (mean ± SE) was significantly greater (P < 0.001) from consumption of the guideline based diets (0.508 ± 0.003 lg/kg/day) than from consumption of the Western diets (0.441 ± 0.003 lg/kg/day). Guideline based diets contained less acrylamide contributed by French fries and potato chips than Western diets. Overall acrylamide intake, however, was higher in guideline based diets as a result of more frequent breakfast cereal intake. This is believed to be the first example of a risk assessment that combines probabilistic techniques with linear programming and results demonstrate that linear programming techniques can be used to model specific diets for the assessment of toxicological and nutritional dietary components.
Type
Article
Description
The article of record as published may be found at http://dx.doi.org/10.1016/j.fct.2011.11.006
Series/Report No
Department
Operations Research
Organization
Naval Postgraduate School (U.S.)
Identifiers
NPS Report Number
Sponsors
Funder
Format
7 p.
Citation
Journal of Food and Chemical Toxicology, v. 50, 2012, pp. 877-883.
Distribution Statement
Approved for public release; distribution is unlimited.
Rights
This publication is a work of the U.S. Government as defined in Title 17, United States Code, Section 101. Copyright protection is not available for this work in the United States.
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