Surviving the 'storm': expanding public health's capabilities in response to the increasing threats posed by novel, pandemic strain viruses
Mackie, Daniel P.
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The recent emergence of two separate outbreaks of two new viruses has generated renewed interest in the threat of pandemics. For a significant portion of the total fatalities associated with these infections the cause of death was due to an over-reaction of an infected body’s immune system. This research explores possible pharmaceutical interventions that would help expand the list of options public health could employ in a response. For inclusion in state stockpiles, medications must meet three specific criteria: medical efficacy, cost, and logistical considerations. We identified four medications that could be employed (three statins - atorvastatin, simvastatin, and gemfibrozil and an antiviral – ribavirin) and present options for their inclusion into state stockpiles. Through this research we have attempted to open a dialogue with other federal and state planners as they wrestle with the same challenges within their home agencies.
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